The island made up of two volcanoes, located in Lake Nicaragua

Volcán Concepcíon and Volcán Maderas
The Port of Moyogalpa, view from the ferry

Moyogalpa is the entry-point for Ometepe, and is the largest village here. The ferry runs from San Jorge to Moyogalpa several times each day, or you can negotiate a private lancha at the port in San Jorge if you’d like! I’d recommend staying in Moyogalpa if you want to experience the village with several restaurants and a choice of hostels/hotels. More history and info on Moyogalpa here.

My first (and so far, only) trip to Ometepe was to a mostly self-sufficient Eco Lodge near Balgüe, so Casey and I hopped off the ferry in Moyogalpa, caught the bus (schedule here) to Altagracia where we then switched to a different bus to continue on to Balgüe! The villages on the island are quite small, so make sure you’re paying attention or you’ll miss your stop. We spent two nights in the rustic lodging (compost toilet outhouses, mosquito nets, and outdoor shower) and thoroughly enjoyed our time! The guesthouses are located on a permaculture farm, where you have access to the gardens (fruits and salad greens) and the outdoor kitchen. The hike up Maderas is nearby too, just past the neighboring finca. We were able to set up that hike with the host and had the trail almost completely to ourselves! Note: we had to sign in at the entrance of the trail, as they make sure everyone makes it back down safely.

Much more detailed info about Ometepe, the villages, buses, ferries, hotels here.